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Clinical and Diagnostic Laboratory Immunology, June 2005, p. 793-796, Vol. 12, No. 6
1071-412X/05/$08.00+0     doi:10.1128/CDLI.12.6.793-796.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Opsonization Effects on Mycobacterium avium subsp. paratuberculosis-Macrophage Interactions

J. Hostetter,* R. Kagan, and E. Steadham

Department of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011

Received 15 December 2004/ Returned for modification 4 February 2005/ Accepted 26 March 2005

High antibody titers in ruminants infected with Mycobacterium avium subsp. paratuberculosis correlates with disease progression. Effects of humoral responses during mycobacterial infection are not completely understood. This study suggests that activation status may be an important factor in determining macrophage ability to limit proliferation of opsonized M. avium subsp. paratuberculosis.

* Corresponding author. Mailing address: Department of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames, IA 50011. Phone: (515) 294-0953. Fax: (515) 294-5423. E-mail: jesseh{at}iastate.edu.

Clinical and Diagnostic Laboratory Immunology, June 2005, p. 793-796, Vol. 12, No. 6
1071-412X/05/$08.00+0     doi:10.1128/CDLI.12.6.793-796.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.





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