Clinical and Diagnostic Laboratory Immunology, September 2001, p. 1036-1038, Vol. 8, No. 5
Laboratorio de Inmunofarmacologia, Facultad
de Medicina, UBA,1 Academia Nacional de
Medicina,2 and Hospital
Muñiz,3 Buenos Aires, Argentina
Received 18 January 2001/Returned for modification 22 February
2001/Accepted 7 June 2001
In patients with chronic paracoccidioidomycosis (n = 10), levels of tumor necrosis factor alpha, interleukin-10, and
interleukin-2 in serum, measured by enzyme-linked immunosorbent assay
(in picograms per milliliter, as mean ± standard error of the
mean), were higher than in normal controls (n = 8):
186 ± 40 versus 40 ± 7 (P < 0.05), 203 ± 95 versus 20 ± 8 (P = 0.001), and
96.3 ± 78.57 versus 1.19 ± 1.19 (P = 0.045), respectively. Gamma interferon and interleukin-4 levels were
similar in patients and controls.
1071-412X/01/$04.00+0 DOI: 10.1128/CDLI.8.5.1036-1038.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.
High Serum Interleukin-10 and Tumor Necrosis Factor
Alpha Levels in Chronic Paracoccidioidomycosis
*
Corresponding author. Mailing address:
Immunopharmacology Lab, Department of Pharmacology, School of Medicine
(UBA), Paraguay 2155, Piso 16, 1121 Buenos Aires, Argentina. Phone and
fax: (5411) 4964-0505. E-mail: rdiez{at}fmed.uba.ar.
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