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Clinical and Diagnostic Laboratory Immunology, January 2000, p. 122-124, Vol. 7, No. 1
1071-412X/0/$04.00+0

Evaluation of the Quantiplex Human Immunodeficiency Virus Type 1 RNA 3.0 Assay in a Tertiary-Care Center

Howard Gale*

Infectious Diseases Section, Medical Service, Veterans Affairs Medical Center, Washington, D.C.

Received 19 July 1999/Returned for modification 25 August 1999/Accepted 14 September 1999

The Quantiplex human immunodeficiency virus type 1 RNA 3.0 Assay (bDNA) (Bayer Diagnostics, Walpole, Mass.) produced linear and reproducible (intra-assay and interassay) results over its quantification range of 50 to 500,000 copies/ml of plasma with 96% specificity. A threefold or 0.5-log10 change or greater was clinically significant for serial patient samples.

* Mailing address: I. D. Section (151B), Veterans Affairs Medical Center, 50 Irving St. NW, Washington, DC 20422. Phone: (202) 745-8301. Fax: (202) 745-8432. E-mail: gale.howard{at}washington.va.gov.

Clinical and Diagnostic Laboratory Immunology, January 2000, p. 122-124, Vol. 7, No. 1
1071-412X/0/$04.00+0




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