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Clinical and Diagnostic Laboratory Immunology, July 1999, p. 624-626, Vol. 6, No. 4
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Total Immunoglobulin E Levels and Dengue Infection on San Andrés Island, Colombia

María José Míguez-Burbano,1,2 Carlos A. Jaramillo,1 Carol J. Palmer,2,* Gail Shor-Posner,2 Luz Stella Velásquez,1 Hong Lai,2 and Marianna K. Baum2

Institute of Virology, Colombian School of Medicine, Bogotá, Colombia,1 and Center for Disease Prevention, University of Miami School of Medicine, Miami, Florida2

Received 8 February 1999/Returned for modification 8 April 1999/Accepted 26 April 1999

An evaluation of total immunoglobulin E (IgE) and dengue serostatus in 168 subjects from San Andrés Island, Colombia, revealed altered levels of IgE in 89% of the population. IgE levels were higher in patients with a history of dengue or with a current secondary or current primary infection than in subjects with no exposure (P = 0.01). Dengue infection accounted for 23% of the variation in IgE levels.

* Corresponding author. Mailing address: University of Miami School of Medicine, Center for Disease Prevention, 1400 NW 10th Ave., 10th Floor (D21), Miami, FL 33136. Phone: (305) 243-4072. Fax: (305) 243-4687. E-mail: gshor{at}mednet.med.miami.edu.

Clinical and Diagnostic Laboratory Immunology, July 1999, p. 624-626, Vol. 6, No. 4
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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Copyright © 1999 by the American Society for Microbiology. All rights reserved.