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Clinical and Diagnostic Laboratory Immunology, July 1999, p. 621-623, Vol. 6, No. 4
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Long-Term Persistence of Immunoglobulin A (IgA) and IgM Antibodies against Human Cytomegalovirus in Solid-Organ Transplant Recipients

Bodo R. Eing,* Horst G. Baumeister, Joachim E. Kuehn, and Guenter May

Institute of Medical Microbiology, Clinical Virology, University of Muenster, Muenster, Germany

Received 30 November 1998/Returned for modification 15 February 1999/Accepted 23 April 1999

The retrospective analysis of 494 solid-organ transplant recipients revealed that during the follow-up period (mean duration, 3.2 years) 184 (88%) of 209 anti-human cytomegalovirus (HCMV) immunoglobulin A (IgA)-positive patients remained IgA positive, as did 128 (74.85%) of 171 anti-HCMV IgM-positive patients. We conclude that anti-HCMV IgA and IgM testing for management of clinically relevant HCMV infections in solid-organ transplant recipients is dispensable.

* Corresponding author. Mailing address: Institute of Medical Microbiology, University of Muenster, von-Stauffenberg-Str. 36, 48151 Muenster, Germany. Phone: (49) 251 7793-156. Fax: (49) 251 7793-104. E-mail: eingb{at}uni-muenster.de.

Clinical and Diagnostic Laboratory Immunology, July 1999, p. 621-623, Vol. 6, No. 4
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.




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Copyright © 1999 by the American Society for Microbiology. All rights reserved.