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Clinical and Diagnostic Laboratory Immunology, January 1999, p. 140-141, Vol. 6, No. 1
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Incidence of Human Immunodeficiency Virus Antibody in a Prenatal Population at a Community Hospital

Thomas S. Alexander,1,2,* Joanne Lee,2 and Belinda Yen-Lieberman3

Department of Pathology and Laboratory Medicine, Summa Health System, Akron, Ohio 443041; Northeastern Universities College of Medicine, Rootstown, Ohio 442722; and Department of Laboratory Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 441063

Received 5 March 1998/Returned for modification 27 May 1998/Accepted 4 November 1998

Prenatal human immunodeficiency virus (HIV) screening may reduce vertical HIV transmission. We screened 4,419 prenatal sera and found 38 repeatedly reactive specimens with an HIV-1-HIV-2 enzyme-linked immunosorbent assay. Western blot analysis confirmed four of these specimens as positive for HIV-1 antibodies. Screening detects previously unidentified HIV infections, but false-positive results may also occur.


* Corresponding author. Mailing address: Dept. of Pathology and Laboratory Medicine, Summa Health System, 525 E. Market St., Akron, OH 44304. Phone: (330) 375-3719. Fax: (330) 375-4874. E-mail: alexandt{at}summa-health.org.


Clinical and Diagnostic Laboratory Immunology, January 1999, p. 140-141, Vol. 6, No. 1
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.






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Copyright © 1999 by the American Society for Microbiology. All rights reserved.