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Clinical and Diagnostic Laboratory Immunology, January 1999, p. 127-129, Vol. 6, No. 1
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Anticytomegalovirus (Anti-CMV) Immunoglobulin G Avidity in Identification of Pregnant Women at Risk of Transmitting Congenital CMV Infection

Tiziana Lazzarotto,1 Patrizia Spezzacatena,1 Stefania Varani,1 Liliana Gabrielli,1 Paola Pradelli,1 Brunella Guerra,2 and Maria Paola Landini1,*

Department of Clinical and Experimental Medicine, Section of Microbiology1 and Second Department of Obstetrics and Gynecology,2 Medical School, University of Bologna, Bologna, Italy

Received 6 July 1998/Returned for modification 17 August 1998/Accepted 30 September 1998

In this work, we show that the determination of the anticytomegalovirus antibody avidity carried out before week 18 of gestation is a helpful tool to identify women for enrollment in prenatal diagnosis. This procedure can identify all pregnant women who will give birth to an infected newborn.

* Corresponding author. Mailing address: Dipartimento di Medicina Clinica Specialistica e Sperimentale, Sezione di Microbiologia, Policlinico S. Orsola, Via Massarenti 9, 40138 Bologna, Italy. Phone: 39.051.341652. Fax: 39.051.341632. E-mail: viroland{at}med.unibo.it.

Clinical and Diagnostic Laboratory Immunology, January 1999, p. 127-129, Vol. 6, No. 1
1071-412X/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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Copyright © 1999 by the American Society for Microbiology. All rights reserved.