This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Mathioudakis, G. Articles by Platsoucas, C. D. Search for Related Content PubMed PubMed Citation Articles by Mathioudakis, G. Articles by Platsoucas, C. D.

 Previous Article

Clinical and Diagnostic Laboratory Immunology, Sep 1996, 616-619, Vol 3, No. 5
Copyright © 1996 by the American Society for Microbiology. All rights reserved.

Selective gamma-chain T-cell receptor gene rearrangements in a patient with Omenn's syndrome: absence of V-II subgroup (V gamma 9) transcripts

G Mathioudakis, RA Good, Y Chernajovsky, NK Day and CD Platsoucas
Department of Immunology, M. D. Anderson Cancer Center, University of Texas, Houston, USA.

Only gamma-chain T-cell receptor transcripts utilizing V-1 subgroup gene segments were found in peripheral blood lymphocytes from a patient with Omenn's syndrome. gamma-Chain T-cell receptor transcripts utilizing the V gamma 9 (V-II subgroup) gene segment were absent in peripheral blood lymphocytes from this patient. V gamma 9 J gamma 1.2 C gamma 1 rearrangements are those primarily found in peripheral blood lymphocytes (70 to 85%) from normal donors.