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Clinical and Diagnostic Laboratory Immunology, 05 1996, 361-362, Vol 3, No. 3
Copyright © 1996 by the American Society for Microbiology. All rights reserved.

Time to peak serum antibody response to influenza vaccine in the elderly

PA Gross, C Russo, M Teplitzky, S Dran, P Cataruozolo and G Munk
Department of Internal Medicine, Hackensack University Medical Center, New Jersey 07601, USA.

The earliest time at which serum antibody peaks following administration of influenza virus vaccine in elderly persons is not clearly defined. We compared the time intervals of 2 and 4 weeks after vaccination. A commercial trivalent vaccine containing the hemagglutinins of influenza viruses A/Texas/36/91(H1N1), A/Shangdong/9/93(H3N2), and B/Panama/45/90 was used. The hemagglutination inhibition antibody titers at 2 weeks after vaccination were identical to the hemagglutination inhibition antibody titers at 4 weeks for all three vaccine components.

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