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 Previous Article

Clinical and Diagnostic Laboratory Immunology, May 1995, 385-386, Vol 2, No. 3
Copyright © 1995 by the American Society for Microbiology. All rights reserved.

Characterization of the recognition site and diagnostic potential of an enterovirus group-reactive monoclonal antibody

A Samuelson, M Forsgren and M Sallberg
Department of Immunology, Microbiology, Pathology and Infectious Diseases, Karolinska Institutet, Huddinge University Hospital, Sweden.

The epitope for a monoclonal antibody reactive against different enteroviruses was characterized. The epitope could be located to residues 40 to 48 of VP1, and the most-essential residues for monoclonal antibody binding coincided with those conserved among the majority of known enteroviruses, indicating a high diagnostic potential.


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Antimicrob. Agents Chemother. Clin. Microbiol. Rev. Infect. Immun.
J. Clin. Microbiol. J. Virol. ALL ASM JOURNALS

Copyright © 1995 by the American Society for Microbiology. All rights reserved.