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Clinical and Diagnostic Laboratory Immunology, 01 1995, 115-117, Vol 2, No. 1
Copyright © 1995 by the American Society for Microbiology. All rights reserved.

Determination of normal human fetal immunoglobulin M levels

DJ Vick, WA Hogge, DE Normansell, BJ Burkett and GM Harbert Jr
Department of Obstetrics & Gynecology, University of Virginia Health Sciences Center, Charlottesville.

Immunoglobulin M (IgM) levels were measured in 198 cord blood samples from 192 apparently normal pregnancies from 24 weeks of gestation to term. Simple linear regression analysis yielded a standard curve for IgM development during pregnancy showing a 0.5 mg/dl increase in IgM per week of gestation. This curve allows the comparison of fetal IgM levels from pregnancies considered to be at risk for intrauterine infection.




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Antimicrob. Agents Chemother. Clin. Microbiol. Rev. Infect. Immun.
J. Clin. Microbiol. J. Virol. ALL ASM JOURNALS

Copyright © 1995 by the American Society for Microbiology. All rights reserved.