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 Previous Article

Clinical and Vaccine Immunology, May 2007, p. 644-647, Vol. 14, No. 5
1071-412X/07/$08.00+0     doi:10.1128/CVI.00032-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Humoral Immune Response after Primary Rubella Virus Infection and after Vaccination{triangledown}

C. Vauloup-Fellous* and L. Grangeot-Keros

Service de Microbiologie Immunologie Biologique, Assistance Publique-Hôpitaux de Paris, Hôpital A. Béclère, Clamart, Faculté de Médecine, Université Paris-Sud, Clamart, France

Received 6 January 2007/ Returned for modification 13 February 2007/ Accepted 28 February 2007

We measured rubella virus immunoglobulin G (IgG) and IgM levels, as well as IgG avidity indexes, in serum samples taken before or after 6 months either after infection or after vaccination. The results obtained indicate that humoral immune responses are different after primary infection and after vaccination. This may have important consequences on the serological diagnosis of rubella virus infection.

* Corresponding author. Mailing address: Service de Microbiologie-Immunologie Biologique, Hôpital Antoine Béclère, 157 av. de la Porte de Trivaux, 92141 Clamart Cedex, France. Phone: (33)1 45 37 42 98. Fax: (33)1 46 32 67 96. E-mail: christelle.vauloup{at}abc.aphp.fr

{triangledown} Published ahead of print on 7 March 2007.

Clinical and Vaccine Immunology, May 2007, p. 644-647, Vol. 14, No. 5
1071-412X/07/$08.00+0     doi:10.1128/CVI.00032-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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