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Clinical and Vaccine Immunology, April 2007, p. 477-480, Vol. 14, No. 4
1071-412X/07/$08.00+0     doi:10.1128/CVI.00463-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Comparison of Mantoux and QuantiFERON TB Gold Tests for Diagnosis of Latent Tuberculosis Infection in Army Personnel{triangledown}

Willeke P. J. Franken,1 Joost F. Timmermans,2 Corine Prins,1 Evert-Jan H. J. Slootman,2 Johan Dreverman,2 Hans Bruins,2 Jaap T. van Dissel,1 and Sandra M. Arend1*

Department of Infectious Diseases, Leiden University Medical Centre, Leiden, The Netherlands,1 Coordinating Center Expert Military Health Care of the Royal Dutch Armed Forces, Hollandse Rading, The Netherlands2

Received 11 December 2006/ Returned for modification 20 January 2007/ Accepted 7 February 2007

The tuberculin skin test (TST) was compared with QuantiFERON-TB Gold in-tube (QFT-GIT) test for the diagnosis of tuberculosis in non-Mycobacterium bovis BCG-vaccinated military personnel. Among subjects positive by TST, 44.4% of recruits were positive by QFT-GIT compared with 11.5% subjects tested after missions abroad, suggesting that most TST conversions in the latter group were caused by nontuberculous mycobacteria.

* Corresponding author. Mailing address: Department of Infectious Diseases, C5-P 39, Leiden University Medical Centre, P.O. Box 9600, 2300 RC Leiden, The Netherlands. Phone: 31 71 5262613. Fax: 31 71 526 6758. E-mail: s.m.arend{at}lumc.nl

{triangledown} Published ahead of print on 14 February 2007.

Clinical and Vaccine Immunology, April 2007, p. 477-480, Vol. 14, No. 4
1071-412X/07/$08.00+0     doi:10.1128/CVI.00463-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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