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Clinical and Vaccine Immunology, October 2007, p. 1384-1386, Vol. 14, No. 10
1071-412X/07/$08.00+0     doi:10.1128/CVI.00356-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Seroincidence of Recent Human Immunodeficiency Virus Type 1 Infections in China{triangledown}

Yao Xiao,1 Yan Jiang,1* Jigang Feng,1 Wenyan Xu,1 Minjie Wang,1 Ellen Funkhouser,2 Sten H. Vermund,3 and Yujiang Jia3*

National AIDS Reference Laboratory, National Center for AIDS & STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, People's Republic of China,1 Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama 35294-0022,2 Institute for Global Health and Department of Pediatrics, School of Medicine, Vanderbilt University, Nashville, Tennessee 37232-02423

Received 18 September 2006/ Returned for modification 13 March 2007/ Accepted 25 July 2007

A subtype B, E, and D immunoglobulin G capture immunoassay shows promise as a tool for estimating human immunodeficiency virus type 1 seroincidence from cross-sectional surveys, but the test-specific limitations suggest that an adjustment is necessary, and further validation of the assay with populations with divergent subtypes is needed.

* Corresponding author. Mailing address for Yan Jiang: National AIDS Reference Laboratory, National Center for AIDS & STD Control and Prevention, Chinese Center for Disease Control and Prevention, Room 909, 27 Nanwei Road, Beijing 100050, P.R. China. Phone and fax: (86-10)-63024898. E-mail: jiangyan03{at}263.net. Mailing address for Yujiang Jia: Institute for Global Health, Vanderbilt University School of Medicine, 2215 Garland Avenue, Light Hall 319, Nashville, TN 37232-0242. Phone: (615) 322-9374. Fax: (615) 322-9400. E-mail: yujiang.jia{at}vanderbilt.edu

{triangledown} Published ahead of print on 1 August 2007.

Clinical and Vaccine Immunology, October 2007, p. 1384-1386, Vol. 14, No. 10
1071-412X/07/$08.00+0     doi:10.1128/CVI.00356-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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