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 Previous Article

Clinical and Vaccine Immunology, January 2006, p. 162-164, Vol. 13, No. 1
1071-412X/06/$08.00+0     doi:10.1128/CVI.13.1.162-164.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Neutralizing and Hemagglutination-Inhibiting Activities of Antibodies Elicited by the 2004-2005 Influenza Vaccine against Drifted Viruses

Filippo Ansaldi,* Sabrina Bacilieri, Federica Banfi, Paolo Durando, Laura Sticchi, Giancarlo Icardi, and Roberto Gasparini

Department of Health Sciences, University of Genoa, Genoa, Italy

Received 5 August 2005/ Returned for modification 18 October 2005/ Accepted 1 November 2005

Evaluation of the antibody responses induced by the 2004-2005 influenza vaccine strain against the homologous variant, the 2004-2005 field isolates, and a previous circulating strain showed that a correlation between neutralizing and hemagglutination-inhibiting activities exists only when the antigen is very close to the vaccine strain.

* Corresponding author. Mailing address: Department of Health Sciences, University of Genoa, Via Pastore 1, 16100 Genoa, Italy. Phone: 390103538503. Fax: 390103538407. E-mail: filippo.ansaldi{at}unige.it.

Clinical and Vaccine Immunology, January 2006, p. 162-164, Vol. 13, No. 1
1071-412X/06/$08.00+0     doi:10.1128/CVI.13.1.162-164.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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