CVI
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Prince, H. E.
Right arrow Articles by Stramer, S. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Prince, H. E.
Right arrow Articles by Stramer, S. L.
Clinical and Diagnostic Laboratory Immunology, September 2005, p. 1123-1126, Vol. 12, No. 9
1071-412X/05/$08.00+0     doi:10.1128/CDLI.12.9.1123-1126.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Utilization of Follow-Up Specimens from Viremic Blood Donors To Assess the Value of West Nile Virus Immunoglobulin G Avidity as an Indicator of Recent Infection

Harry E. Prince,1* Mary Lapé-Nixon,1 Michael P. Busch,2 Leslie H. Tobler,2 Gregory A. Foster,3 and Susan L. Stramer3

Focus Diagnostics, Cypress, California,1 Blood Systems Research Institute, San Francisco, California,2 American Red Cross Blood Services, Gaithersburg, Maryland3

Received 21 April 2005/ Returned for modification 24 May 2005/ Accepted 15 June 2005

The value of West Nile virus immunoglobulin G avidity for distinguishing recent from past infection was investigated using 348 follow-up specimens from 170 viremic blood donors. Low avidity accurately indicated infection within the previous 4 months. However, due to rapid avidity maturation in some individuals, high avidity did not accurately indicate past infection.

* Corresponding author. Mailing address: Focus Diagnostics, 5785 Corporate Avenue, Cypress, CA 90630. Phone: (714) 503-2047. Fax: (714) 484-1296. E-mail: hprince{at}focusdx.com.

Clinical and Diagnostic Laboratory Immunology, September 2005, p. 1123-1126, Vol. 12, No. 9
1071-412X/05/$08.00+0     doi:10.1128/CDLI.12.9.1123-1126.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.





Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Antimicrob. Agents Chemother. Clin. Microbiol. Rev. Infect. Immun.
J. Clin. Microbiol. J. Virol. ALL ASM JOURNALS

Copyright © 2005 by the American Society for Microbiology. All rights reserved.