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 Previous Article

Clinical and Diagnostic Laboratory Immunology, September 2004, p. 983-985, Vol. 11, No. 5
1071-412X/04/$08.00+0     DOI: 10.1128/CDLI.11.5.983-985.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Age-Specific Immune Response to HspA in Helicobacter pylori-Positive Persons in Mexico

Peter P. Eamranond,1 Javier Torres,2 Onofre Muñoz,2 and Guillermo I. Pérez-Pérez3*

Vanderbilt University School of Medicine, Nashville, Tennessee,1 Unidad de Investigacion Medica en Enfermedades Infecciosas y Parasitarias, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico,2 Department of Medicine and Microbiology, New York University School of Medicine, New York, New York3

Received 6 November 2003/ Returned for modification 7 January 2004/ Accepted 16 July 2004

The immune response to heat shock protein A (HspA) in Helicobacter pylori-positive adults increases with age in developed countries. This response has not been studied with children or in developing countries (G. I. Pérez-Pérez, J. M. Thiberge, A. Labigne, and M. J. Blaser, J. Infect. Dis. 174:1046-1050, 1996). As determined by using a specific enzyme-linked immunosorbent assay, HspA seropositivity among 592 individuals in Mexico was <10% in children and increased to >40% in adults.

* Corresponding author. Mailing address: Department of Medicine, New York University School of Medicine, 550 First Ave. 16NBH, New York, NY 10016. Phone: (212) 263-4101. Fax: (212) 252-7164. E-mail: perezg02{at}med.nyu.edu.

Clinical and Diagnostic Laboratory Immunology, September 2004, p. 983-985, Vol. 11, No. 5
1071-412X/04/$08.00+0     DOI: 10.1128/CDLI.11.5.983-985.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.





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