This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Mattsson, E. Articles by Egesten, A. Search for Related Content PubMed PubMed Citation Articles by Mattsson, E. Articles by Egesten, A.

Peptidoglycan Induces Mobilization of the Surface Marker for Activation Marker CD66b in Human Neutrophils but Not in Eosinophils

Department of Infectious Diseases,¹ Department of Cell and Molecular Biology, University Hospital, Lund University, Lund,² Department of Medical Microbiology, Malmö University Hospital, Lund University, Malmö, Sweden³

Received 3 September 2002/ Returned for modification 21 November 2002/ Accepted 16 January 2003

Peptidoglycan from Staphylococcus aureus mobilized CD66b in human neutrophils but did not upregulate surface activation markers in eosinophils. In addition, Toll-like receptor 2, implicated in the recognition of peptidoglycan, was detected on the surface of resting neutrophils but not on eosinophils. These findings suggest roles for neutrophils but not eosinophils in innate recognition of peptidoglycan.