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Clinical and Diagnostic Laboratory Immunology, Mar 1994, 244-246, Vol 1, No. 2
Copyright © 1994 by the American Society for Microbiology. All rights reserved.

Augmentation of anti-influenza virus hemagglutinin antibody production by Peyer's patch cells with Bifidobacterium breve YIT4064

H Yasui, N Nagaoka and K Hayakawa
Yakult Central Institute for Microbiological Research, Tokyo, Japan.

Bifidobacterium breve YIT4064 was tested an an adjuvant for oral influenza vaccine by the murine Peyer's patch cell culture method. The organism augmented production of anti-influenza virus hemagglutinin immunoglobulin A antibody by Peyer's patch cells in response to addition of hemagglutinin. These antibodies may be disseminated to the respiratory mucosal tissue and prevent influenza virus infection.


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Antimicrob. Agents Chemother. Clin. Microbiol. Rev. Infect. Immun.
J. Clin. Microbiol. J. Virol. ALL ASM JOURNALS

Copyright © 1994 by the American Society for Microbiology. All rights reserved.