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Clinical and Diagnostic Laboratory Immunology, Jan 1994, 117-120, Vol 1, No. 1
Copyright © 1994 by the American Society for Microbiology. All rights reserved.

Differential elevation of circulating interleukin-1 beta, tumor necrosis factor alpha, and interleukin-6 in AIDS-associated cachectic states

L Belec, D Meillet, A Hernvann, G Gresenguet and R Gherardi
Service de Microbiologie (Virologie), Hopital Broussais, Paris, France.

Elevation of serum interleukin-1 beta (IL-1 beta) levels, and to a lesser degree tumor necrosis factor alpha levels, was found in cachectic human immunodeficiency virus (HIV)-infected African patients without concurrent opportunistic infection or neoplasia (HIV wasting syndrome). A heterogeneous pattern of elevations of cytokine levels, including mild elevations of IL-1 beta and pronounced elevations of IL- 6 levels, was found in other cachectic states.


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Antimicrob. Agents Chemother. Clin. Microbiol. Rev. Infect. Immun.
J. Clin. Microbiol. J. Virol. ALL ASM JOURNALS

Copyright © 1994 by the American Society for Microbiology. All rights reserved.